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Modafinil is a wakefulness-promoting drug. The active ingredients found in this drug, during blind studies, have proven to help promote alertness in certain individuals under certain circumstances.

This drug was originally developed in France by "Michel Jouvet" a renowned neuropsychologist. It elevated the hypothalamic histamine levels and seems to inhibit the actions of the dopamine transporter. It was approved for use in France in 1994. In 1998 the United States Food and Drug Administration (FDA) approved it for the treatment of a few conditions with the United Kingdom following suit in 2002.

The United States (FDA) approved the use of Modafinil for the treatment of narcolepsy, shift work sleep disorder and excessive daytime sleepiness associated with obstructive sleep apnea. These are the only approved conditions the drug is authorized to be prescribed for, although, there are several other uses.

Off-the-label uses showing signs of positive results, Modafinil has been used for a variety of treatments. Some of which include: Memory enhancement, fighting fatigue in multiple sclerosis and fibromyalgia patients, attention deficit hyperactivity disorder, attention deficit disorder, cancer chemo-brain rehab and general depression.

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Several military and law-enforcement agencies from around the world have conducted their own studies into the use of this drug in enhancing the capabilities of their units during heightened and prolonged missions.

This drug has been used by College students and corporate employees to try to gain an edge in performing at a higher level for longer periods of time than they would otherwise be able to perform.

Thus far there are no signs of this drug being habit forming or addictive. Although it seems to have some of the same effects as cocaine or other amphetamines, it has not been classified in the same category and remains legal by prescription. Yet many acquire the drug through street sources or online pharmacies in illegal methods.

The drug does have several side-effects to remain weary of if taking the drug on a routine basis. They include: nausea, headaches, insomnia, elevated liver enzymes, mouth sores and rashes. A possible desired side-effect has been reported as well. Taking this drug has caused sustained weight loss in many individuals.

There does not seem to be enough information available on all the benefits or potential hazards this drug could possess. However, the future seems to be a promising one for the uses and advances possible with this drug if taken properly and monitored under the care of a physician. This drug is currently available in the United States by Cephalon Inc.

Cephalon Incorporated bought the rights from the French laboratory that developed Modafinil and later bought the company. They market it as "Provigil" and have sold it in the United States for over 15 years.